CID 2000;31:1-14
Table 4. Recommended therapy for patients with Lyme disease.
Indication Treatment Duration
Tick bite None recommended observe
Erythema migrans Oral regimena 14-21 A-I
Acute neurological disease
Meningitis or radiculopathy Parenteral regimena 14-28 B-II/A-I
Cranial-nerve palsy Oral regimen 14-21
1st or 2d degree heart block Oral regimen 14-21 B-II
3d degree heart block Parenteral regimena 14-21 B-III
Arthritis without neurological disease Oral regimen 28 B-II
Recurrent arthritis after oral regimen Oral regimen or 28 B-III
Persistent arthritis after 2 courses of antibiotics Symptomatic therapy B-II
CNS or peripheral nervous system disease Parenteral regimen 14-28 B-II
Chronic Lyme disease or postLyme disease syndrome Symptomatic therapy