Conclusions
Antibiotics are effective in severe forms of AECB
Clinical criteria are useful in the determination of the indication
Currently the “best” guidelines are the GOLD guidelines, although not restrictive enough
Antibiotics should at least be effective against M. catarrhalis; H. influenzae and S.pneumoniae
It is not clear at what resistance level (%) guidelines should leave out an antibiotic
The Netherlands should probably revise their guidelines