Recommendations non-pregnant women (1)
The efficacy of fluoroquinolones for empiric therapy has been established (1++, A).
Oral therapy is proposed for patients without clinical signs of severe sepsis (1++, A). Outpatient treatment with oral fluoroquinolones is safe in absence of severe sepsis and renal insufficiency, and with the ability to take oral medication (1+, B).
First generation fluoroquinolones (FQ1), such as norfloxacine, are not recommended because of their low serum concentration (4, D).
Association of an aminoglycoside is not recommended in absence of severe sepsis (1+, B).
Co-trimoxazole, ampicillin and first generation cephalosporins cannot be recommended as empiric therapy due to the high level of resistance in many regions of Belgium.
MILD PYELONEPHRITIS - empirical therapy