From norfloxacin to the other 1st generation fluoroquinolones: pefloxacin

-

H

3

C

N

pefloxacin *

Add a methyl

to still increase

half-life

* Ger. pat. 2,840,910 to  Roger Bellon/Dainippon,1979

O

O

N

C

F

O

-

N

CH

3

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